Methacrylated Collagen (also known as PhotoCol® and Lifeink® 100) is a photocrosslinkable type I collagen for 3D cell culture and bioprinting.
As the most abundant protein in the body, collagen is a key component for cell culture. Collagen methacrylate can be used as a rapidly self-assembling type I collagen to form cross-linked hydrogels for tissue engineering. It has been used with mesenchymal stem cells, fibroblasts, adipose derived stem cells, epithelial cells, and many more.
Collagen methacrylate is useful for forming scaffolds with varying degree of stiffness, by altering collagen concentration or the dose of UV-light exposure. It is also being extensively characterized for its usefulness in 3D bioprinting (extrusion, inkjet, and photolithographic).
Lifeink® 100 has been used for created 3D microniches, as well as for 3D bioprinting human corneas.